3M™ Skin and Nasal Antiseptic (Povidone-Iodine Solution 5% w/w [0.5% available iodine] USP) Patient Preoperative Skin Preparation 192401, 4 mL

Assurance - Reduces bacterial counts in the nares,3 including S. aureus by 99.5%, so you know you're helping address another variable in the fight against surgical site infections
Control - Works within one hour and easily fits within your facility preoperative process, so you can ensure compliance
Science - Strong research and development created an effective, patented formula to compensate for the unique physiology of the nose
Safety - Active ingredient has been used for over 100 years, and has not been shown to lead to resistance4, so it won't impact your antibiotic stewardship
Easy - Antiseptic that does not require special handling and storage
Comfort - Formula is pH balanced to be non-irritating to the nares
Clean - Special formula designed not to dripReferences:
1 3M Skin and Nasal Antiseptic Safety and Efficacy Data, 3M Study-05-011100
2 3M Study 05-011017
3 3M Study-05-011100
4 3M Study 05-011322
Antimicrobial Effectiveness Against Resident Human Nasal Flora, Mainly Staphylococcus aureus, vs. a Saline Control3
Purpose: The purpose of this study (completed in 2009) was to assess the antimicrobial efficacy of 3M Skin and Nasal Antiseptic on the nasal flora of healthy volunteers versus a saline control. The study measured the reduction of S. aureus at 1, 6, and 12-hours post treatment application. The reduction of total bacteria was also measured at these time points. Product acceptability data was collected from the subjects using a questionnaire.
Method: Thirteen to eighteen subjects (depending on time point) applied 3M Skin and Nasal Antiseptic following the instructions for nasal application. Seven to nine subjects (depending on time point) applied the 0.9% saline control.
One at a time, the foam-tipped applicators were saturated with the appropriate solution using a vigorous stirring motion for at least 10 seconds. The subject’s nostrils were prepped for 30 seconds each using separate applicators. This process was then repeated using two additional applicators for a total application time of 1 minute per nare (2 minutes total). Post-prep samples were taken at 1-hour, 6-hours, and 12-hours from the nares. Baseline samples were taken before the application of the prep or control.
Results: 3M Skin and Nasal Antiseptic killed 99.5% of S. aureus within 1-hour and maintained the 99.5% kill for at least 12-hours post-prep. 3M Skin and Nasal Antiseptic killed 99.2% of the total bacteria within 1-hour and maintained a 98.8% kill for at least 12-hours post-prep. The S. aureus count and the total bacterial count for 3M Skin and Nasal Antiseptic were significantly different from baseline using a paired t-test (P-value ≤ 0.0004). 3M Skin and Nasal Antiseptic showed significantly more S. aureus reduction as well as more total bacterial reduction than control using a 2-sample t-test (P-value ≤ 0.02).Read the summary of seven clinical studies. Get the evidence.
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